Factors Affecting the Price of Defitelio

Defitelio (defibrotide), used to treat severe veno-occlusive disease, has a price shaped by key factors. High R&D costs, from developing this nucleotide polymer to clinical trials for rare post-transplant complications, drive pricing. Patent protection grants Jazz Pharmaceuticals market exclusivity, allowing premium rates without generic competition.

Factors Affecting the Price of Defitelio

Production complexity, including specialized manufacturing and strict quality control for its injectable form, adds costs. Limited market demand due to the rarity of the condition it treats further sustains high prices. Regional healthcare policies, insurance coverage, and access programs also influence the final cost borne by patients.