Adagrasib can cause serious side effects like gastrointestinal issues, liver problems, and cardiac concerns. Patients should be monitored closely during treatment.

Warnings and Precautions

Gastrointestinal issues: Including nausea, diarrhea, and vomiting. Severe cases may require dose adjustments or discontinuation.

Cardiac issues: QTc prolongation is possible, increasing the risk of serious arrhythmias. Monitoring of heart activity is recommended.

Liver toxicity: Liver function tests should be performed before and during treatment.

Lung issues: Adagrasib may cause pulmonary inflammation leading to fatal outcomes.