Before taking Filspari(Sparsentan)

Sparsentan requires caution due to risks of hepatotoxicity, embryo-fetal toxicity, hypotension, kidney injury, and hyperkalemia.

Warnings and Precautions for Sparsentan

Patients must undergo liver function tests before starting Sparsentan and periodically during treatment. It is contraindicated in pregnancy due to embryo-fetal toxicity. Sparsentan can cause hypotension, acute kidney injury, hyperkalemia, and fluid retention. Careful monitoring and treatment adjustment are necessary for these risks

Sparsentan(Filspari)
Adult patients with primary immunoglobulin A nephropathy (IgAN) who are at risk of rapid disease progression.
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