Before taking Orserdu(Elacestrant)

ORSERDU™ may cause lipid abnormalities, fetal harm, and should be avoided in patients with severe hepatic impairment.  

Precautions for Using ORSERDU™

Before starting ORSERDU™, patients should be screened for lipid abnormalities, as the drug may cause increased cholesterol and triglyceride levels. Regular monitoring of lipid profiles is recommended during treatment. Additionally, ORSERDU™ is contraindicated in pregnant women due to the potential for embryo-fetal toxicity. 

Effective contraception is advised during treatment. Severe hepatic impairment (Child-Pugh C) is a contraindication for using ORSERDU™, while for moderate hepatic impairment (Child-Pugh B), a dosage reduction is necessary. Concomitant use with strong or moderate CYP3A4 inducers and inhibitors should be avoided due to possible drug interactions.

Elacestrant(Orserdu)
Advanced or metastatic breast cancer that is ER-positive, HER2-negative, and has ESR1 mutations.
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