Amlodipine is a long-acting dihydropyridine calcium channel blocker, composed of amlodipine besylate monohydrate. It provides a convenient treatment option for patients with hypertension and angina pectoris.
Indications of Amlodipine
Hypertension Treatment
Amlodipine orally disintegrating tablets are indicated for the treatment of all types of hypertension and can be used alone or in combination with other antihypertensive drugs.
Clinical studies have shown that once-daily administration can effectively maintain 24-hour blood pressure control. In patients with mild to moderate hypertension, it reduces the standing blood pressure by an average of approximately 12/6 mmHg and the supine blood pressure by an average of approximately 13/7 mmHg.
Coronary Heart Disease Treatment
Chronic stable angina pectoris: It is indicated for the long-term symptomatic management of chronic stable angina pectoris and can be used as monotherapy or in combination with other anti-anginal drugs such as nitrates and beta-blockers.
Vasospastic angina pectoris (Prinzmetal's or variant angina pectoris): It has a significant therapeutic effect on confirmed or suspected vasospastic angina pectoris, and restores blood flow by inhibiting coronary artery spasm.
Specifications and Properties of Amlodipine
Specification System
Three specifications are available: 2.5 mg, 5 mg, and 10 mg, which are equivalent to 2.5 mg, 5 mg, and 10 mg of amlodipine respectively.
Appearance Characteristics
2.5 mg specification: White, round, biconvex tablets, engraved with "ADP2.5" on one side and "ODT" on the other side.
5 mg specification: Light yellow, round, biconvex tablets, engraved with "ADP5" on one side and "ODT" on the other side.
10 mg specification: Pink, round, biconvex tablets, engraved with "ADP10" on one side and "ODT" on the other side.
Excipient Ingredients
It contains inactive ingredients such as hydroxypropyl cellulose, iron oxide red (for 10 mg tablets only), iron oxide yellow (for 5 mg tablets only), magnesium stearate, menthol, silicified microcrystalline cellulose, and sucralose.
Storage Conditions of Amlodipine
Routine Storage Requirements
Storage temperature: 20°C to 25°C (68°F to 77°F).
Permissible short-term storage temperature: 15°C to 30°C (59°F to 86°F).
Storage conditions must comply with the USP (United States Pharmacopeia) controlled room temperature standards.
Special Storage Precautions
It should be stored in a sealed and light-resistant container.
Avoid storage in humid environments such as bathrooms.
Ensure the medicine is kept out of the reach of children.
