Vadadustat (Vafseo) is an oral medication used to treat anemia in dialysis patients with chronic kidney disease (CKD), and must be used strictly as directed by a doctor.

How to Purchase Vadadustat (Vafseo)

Overseas Purchase

Patients may choose to consult and purchase the medication at hospital pharmacies or licensed drugstores in countries or regions where Vadadustat is marketed.

Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.

Purchase through Medical Service Institutions

Patients can consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.

These institutions usually provide legal import channels and can offer professional consultation and guidance.

Precautions for Purchasing Vadadustat (Vafseo)

Contraindications and Risk Assessment

Absolute Contraindications: Contraindicated in patients allergic to vadadustat and patients with uncontrolled hypertension.

High-Risk Populations: Avoid use in patients with a history of myocardial infarction or stroke within the recent 3 months; not recommended for patients with active malignant tumors, liver cirrhosis, or acute liver disease.

Medication Monitoring Requirements

Hemoglobin (Hb) Monitoring: Test once every 2 weeks in the initial stage of treatment, and once a month after Hb levels stabilize. If the Hb increase rate exceeds 1 g/dL every 2 weeks or Hb levels exceed 11 g/dL, suspend the medication.

Liver Function Monitoring: Test alanine transaminase (ALT) and aspartate transaminase (AST) once a month within the first 6 months of medication use. Discontinue the medication if there is a persistent increase (exceeding 3 times the normal value) or accompanied by elevated bilirubin.

Drug Interactions

Iron Supplements and Phosphate Binders: Administer with an interval of 1 hour to avoid affecting absorption.

Statins: Dosage adjustment is required (e.g., simvastatin ≤ 20 mg/day) to prevent adverse reactions.

How to Identify the Authenticity of Vadadustat (Vafseo)

Package and Label Verification

Tablets are available in three strengths: 150 mg (white, round), 300 mg (yellow, oval), and 450 mg (pink, oval). All tablets are marked with "VDT" and the corresponding dosage number.

The outer package must be completely sealed, and labeled with the batch number, expiration date, and manufacturer information (Akebia Therapeutics, Inc. / Amgen).

Drug Traceability and Storage

Official Verification: Contact the manufacturer via the traceability code on the package to verify authenticity.

Storage Conditions: Store at 20°C - 25°C away from light; temperature control records must be provided during transportation.

Identification of Abnormal Situations

Differences in Adverse Reactions: Counterfeit drugs may cause severe liver damage not recorded in the instruction manual or result in ineffective treatment.

Abnormal Packaging: Be alert to blurred labels, inconsistent tablet color/shape, or damaged seals.