Tretinoin Capsules are a prescription medication used for the treatment of acute promyelocytic leukemia (APL). Due to their specific properties and potential risks, extra caution is required during purchase and use.
How to Purchase Tretinoin Capsules
Overseas Purchase
Patients may choose to consult and purchase Tretinoin Capsules at hospital pharmacies or formal drugstores in countries or regions where the medication has been launched.
Since drug prices may be affected by factors such as regional differences and exchange rate fluctuations, patients need to make a budget and plan in advance before purchasing.
Purchase through Medical Service Institutions
Patients can consult domestic overseas medical service institutions that cooperate with international pharmacies or pharmaceutical companies.
These institutions can usually provide legal import channels and offer professional consultation and guidance.
Precautions for Purchasing Tretinoin Capsules
Strictly Use as Prescribed by Doctors
The recommended dosage of Tretinoin Capsules is 22.5mg/m² taken orally twice a day until complete remission is achieved.
The medication should be used under strict medical monitoring. Treatment should be discontinued when complete remission is achieved within 30 days or after 90 days of treatment (whichever comes first).
Precautions for Special Populations
Contraindicated in Pregnant Women: Tretinoin Capsules can cause embryo-fetal toxicity and malformations. Women of childbearing age must undergo a pregnancy test before starting treatment, and the medication can only be used if the result is negative.
Lactating Women: Breastfeeding should not be done during treatment and within 1 week after the last dose.
Use in Children: Children over 1 year old may use the medication, but close monitoring is required for potential severe headaches and increased intracranial pressure.
Use in Elderly Patients: In clinical studies, 21% of patients were 60 years old or above, and no difference in efficacy was observed compared with younger patients.
Warnings about Drug Interactions
Avoid concurrent use with potent CYP3A inhibitors or inducers.
Avoid simultaneous use with other products that may cause increased intracranial pressure (e.g., tetracyclines).
Avoid simultaneous use with vitamin A.
Avoid simultaneous use with antifibrinolytic agents (e.g., tranexamic acid, aminocaproic acid, or aprotinin).
Methods to Identify Genuine vs. Counterfeit Tretinoin Capsules
Packaging Identification
The 10mg specification comes as two-color capsules (orange-yellow and reddish-brown in longitudinal distribution).
The capsules are printed with "10mg" in black font.
The packaging bottle should be equipped with a child-resistant closure.
The bottle is labeled with NDC# 61269-750-10 (for the 100-capsule package).
Drug Properties
The content of genuine Tretinoin Capsules is a yellow to light orange crystalline powder, which is almost insoluble in water, slightly soluble in ethanol (96%), and slightly soluble in dichloromethane.
