Vosoritide, also known as vosoritide, is an innovative drug for children with achondroplasia and open epiphyses. Its unique efficacy has attracted widespread attention in the medical community. For the majority of patients and their families, how to safely and legally purchase genuine vosoritide has become their primary concern. Then, what is the price of vosoritide?
What is the price of vosoritide?
Vosoritide is produced by BioMarin in the United States, with a specification of 0.56mg*1 vial, and the price is approximately $9,617 per box. It has not been marketed in China.
Contact the manufacturer directly
For patients in need of purchasing vosoritide, the most direct and safe way is to contact the manufacturer through official channels. Patients or their families can obtain detailed information about vosoritide through BioMarin's official website. After confirming the purchase intention, they can fill in the information according to the website guidelines and complete the payment process.
Formal medical institutions
Patients can also choose to go to formal medical institutions to purchase vosoritide under the guidance of professional doctors. Before purchasing, the doctor will conduct a comprehensive assessment of the patient's condition, determine whether vosoritide is suitable for the patient, and explain the medication method in detail.
Side effects of vosoritide
Although vosoritide has significant efficacy in the treatment of children with achondroplasia and open epiphyses, it may also cause some adverse reactions.
Common adverse reactions
The most common adverse reactions include injection site erythema, injection site swelling, rash, vomiting, injection site urticaria, joint pain, hypotension, and gastroenteritis. These adverse reactions are usually mild and gradually alleviate with the extension of medication time.
Risk of hypotension
Transient decreases in blood pressure have been observed in clinical studies of vosoritide, which may be related to the drug's impact on the cardiovascular system. To reduce the risk of hypotension and its related symptoms, patients should take sufficient food and fluids before medication and drink about 240 to 300ml of fluids within one hour before injection.
Dosage and administration of vosoritide
The recommended dose of vosoritide is based on the patient's actual weight, and it is advisable to consult a professional doctor to determine the specific dose.
Recommended dosage and administration method
Vosoritide is administered subcutaneously once a day, preferably at approximately the same time each day. The dosage is determined according to the patient's actual weight and the concentration of reconstituted vosoritide (0.8mg/mL or 2mg/mL). Before administration, vosoritide must be reconstituted using the provided dilution syringe containing sterile water for injection (USP). Strict operating specifications must be followed during the reconstitution process.
Handling of missed doses
If a dose of vosoritide is missed, the patient can take the missed dose within 12 hours of the scheduled administration time. If more than 12 hours have passed, the missed dose should be skipped, and the next daily dose should be taken according to the usual dosage schedule. Patients should try their best to avoid missing doses to prevent affecting the therapeutic effect.
If it is really impossible to take the medication on time, the patient should promptly report to the doctor and seek professional advice.
