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   What are the side effects of Enbrel?
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Jul 25, 2025

Enbrel is a drug commonly used to treat rheumatoid arthritis, ankylosing spondylitis, and psoriasis. Although it often performs well in treating these diseases, some side effects may occur during use. This article will discuss the common side effects of Enbrel, which include local reactions at the injection site and other adverse reactions such as headache, dizziness, rash, insomnia, cough, abdominal pain, and upper respiratory tract infection.

What are the side effects of Enbrel?

The following editor will accept the side effects of Enbrel in detail to provide you with a reference.

Local reactions at the injection site

One of the common side effects of Enbrel is local reactions at the injection site. These reactions are usually mild to moderate erythema, itching, pain, and swelling. These reactions are usually short-lived and usually resolve on their own within a few days after injection.

Headache and dizziness

The use of Enbrel may cause headaches and dizziness. These discomforts may be caused by the effects of the drug on the central nervous system. If persistent or severe headaches or dizziness occur, it is recommended to consult a doctor for further evaluation and treatment.

Rash

A rash may occur during the use of Enbrel. A rash may be a sign of an allergic reaction, usually manifesting as a rash, itching, or other skin abnormalities. If a rash or other symptoms of an allergic reaction occur, inform your doctor promptly for appropriate treatment and advice.

Insomnia

The use of Etanercept may cause insomnia symptoms. Patients may have difficulty falling asleep or staying asleep at night. If insomnia symptoms seriously affect the quality of life, it is recommended to inform your doctor for appropriate treatment and support.

Cough and upper respiratory tract infection

Some patients may experience respiratory symptoms such as cough and upper respiratory tract infection while using Etanercept. If a persistent or severe cough occurs, or is accompanied by other symptoms of respiratory tract infection, it is recommended to inform your doctor promptly for further evaluation and treatment.

Abdominal pain

Some patients may experience abdominal pain while using Etanercept. Abdominal pain may be related to indigestion or intestinal reactions. If the abdominal pain is severe or lasts for a long time, it is recommended to inform your doctor promptly for further evaluation and treatment.

The side effects listed above are not all possible side effects, and each person's reaction to the drug may be different.

Now that we have learned about the side effects of Enbrel, how should we relieve them if we experience side effects? Let me explain in detail.

How to relieve side effects of Enbrel

If you experience side effects while using Enbrel, here are some possible relief methods:

How to deal with local reactions at the injection site

Gently placing ice packs or cold compresses on the injection site can relieve symptoms such as erythema, pain and swelling. Be careful to avoid rubbing or excessively touching the injection site to avoid aggravating the discomfort. You can also ask your doctor if you can use local soothing agents, such as local anti-inflammatory ointments or antipruritic drugs, to relieve symptoms.

How to deal with headaches and dizziness

Try to avoid overwork and get enough rest and sleep; maintain adequate water intake to avoid headaches that may be caused by dehydration; reduce exposure to light, noise and irritants to reduce the discomfort of headaches and dizziness.

How to deal with rashes

Avoid using irritating skin care products or cosmetics; choose mild and non-irritating cleansers for bathing and avoid excessive friction of the skin; use moisturizers to keep the skin moist to help relieve itching.

How to deal with insomnia

Try to maintain a fixed sleeping and waking time, and develop good sleeping habits; create a quiet, dark, and comfortable sleeping environment, such as blackout curtains and quiet music; avoid consuming caffeine or stimulating food and drinks before bedtime.

How to deal with other adverse reactions

If other adverse reactions occur, such as coughing, abdominal pain, or upper respiratory tract infection, it is recommended to consult a doctor in time. The doctor can give appropriate treatment and advice according to the specific situation.

These relief methods are for reference only, and the specific relief methods should be adjusted according to your specific situation and the doctor's advice. If the side effects are severe or last for a long time, or if you have any concerns, please contact your doctor in time. The doctor will assess the severity of the side effects and give corresponding guidance and treatment.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Enbrel(Etanercept)
Patients with RA, PsA, AS, or PsO.
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