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   Precautions for Enbrel
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Jul 25, 2025

Enbrel is an important biological agent that plays a significant role in the treatment of autoimmune diseases. When using Enbrel, special attention should be paid to some key matters to ensure that it can play a therapeutic role. Before receiving Enbrel treatment, patients should fully understand these precautions and use them correctly under the guidance of doctors to achieve the best treatment effect.

Precautions for Enbrel

Before starting to use Enbrel, both patients and doctors should fully understand and pay attention to its relevant precautions. As an effective biological agent, Enbrel can significantly improve the symptoms of autoimmune diseases, but there are also some aspects that require special attention. These precautions cover multiple aspects from the storage and use of injections, prevention of infection risks, response to allergic reactions, to interactions with other drugs.

1. Temperature adjustment of injections

Before injection, the refrigerated injection should be allowed to reach room temperature before use (approximately 15 to 30 minutes). During the process of reaching room temperature, the protective cover of the needle should not be removed to ensure that the temperature of the injection is appropriate and safe.

2. Careful consideration of infection history

Serious infections have occurred during the use of similar products on the market. If the patient has a history of recurrent infections or a latent disease that is prone to infection, the use of Enbrel should be extremely cautious and should be carried out under the guidance of a doctor.

3. Timely medical treatment for infection tendency

During the use of Enbrel, if the patient has repeated upper respiratory tract infections or other obvious infection tendencies, he should go to the hospital for treatment in time, and the doctor will guide the treatment according to the specific situation to avoid further aggravation of the infection.

4. Discontinuation of drug treatment for severe infection

When severe infection occurs, such as secondary infection of diabetes, tuberculosis infection or sepsis, the patient should stop using Enbrel immediately and seek medical treatment for appropriate treatment in time.

5. Attention and treatment of allergic reactions

When using Enbrel, pay attention to the occurrence of allergic reactions, including angioedema, urticaria, etc. If an allergic reaction occurs, the treatment of Enbrel should be discontinued immediately, and medical treatment should be sought in time for appropriate treatment.

6. Effects of anti-tumor necrosis factor on the immune system

Tumor necrosis factor can regulate inflammation and cellular immune response. When using Enbrel, full consideration should be given to the effects that may affect the patient's anti-infection and malignant tumors, and physical examinations should be performed regularly.

7. Monitoring of liver enzymes during combined medication

When used in combination with nonsteroidal anti-inflammatory drugs or other drugs that may cause liver damage, attention should be paid to changes in liver enzyme levels. If abnormal liver enzymes are elevated, timely assessment should be made based on the patient's disease condition, and Enbrel treatment should be suspended if necessary to protect the liver and reduce enzymes.

8. Avoid vaccination with live vaccines

There is currently no data on the spread of infection in patients who have received Enbrel after receiving live vaccines. To ensure safety, live vaccines should be avoided during the use of Enbrel.

In addition to the above precautions, patients with congestive heart failure should carefully evaluate their condition before use to avoid worsening of the condition. The risk of recurrence of tuberculosis and hepatitis should also be closely monitored, and patients should exclude related infections before use. For patients with alcoholic hepatitis, doctors should carefully evaluate its suitability. Enbrel is not a recommended drug for the treatment of Wegener's granulomatosis, and diabetic patients may need to adjust the dose of hypoglycemic drugs when using it.

Before starting treatment, patients should read the instructions carefully and use Enbrel correctly under the guidance of a doctor to achieve the best treatment effect.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Enbrel(Etanercept)
Patients with RA, PsA, AS, or PsO.
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