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   Recommended dose of Cyclogest (Progesterone suppository)
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Jul 15, 2025

In the field of gynecological medicine, Progesterone (Cyclogest) is a widely used drug, mainly used in the treatment of assisted reproductive technology (ART) and to relieve the symptoms of premenstrual syndrome and postpartum depression. As a natural progestin, Cyclogest has significant effects and certain safety in the treatment of the above-mentioned conditions. But like all drugs, the correct dosage and usage should be followed when using Cyclogest to ensure its optimal efficacy and reduce potential risks.

Recommended dose of Cyclogest (Progesterone suppository)

Dosage for women undergoing assisted reproductive technology (ART) treatment

In women undergoing ART treatment, the recommended dose of Cyclogest is 400 mg twice a day, administered by vaginal insertion. This dose is designed to simulate the Progesterone level in the luteal phase of natural pregnancy to help maintain embryo implantation and early pregnancy. Typically, Cyclogest is used starting on the day of egg retrieval and continued until the 38th day after pregnancy is confirmed.

Dosage for the treatment of PMS and PPD

The dose of Cyclogest may vary from person to person when treating PMS and PPD. The recommended dose is 200 mg once daily or 400 mg twice daily, which can be administered vaginally or rectally. The specific dose and route of administration should be determined based on the patient's specific symptoms and the doctor's advice.

About the side effects of Cyclogest

Although Cyclogest is effective in treating gynecological diseases, it may also cause some side effects. Here are some common side effects:

1. Common side effects (≥10%)

After using Cyclogest, some patients may experience symptoms such as bloating (abdominal swelling), abdominal pain, constipation, drowsiness, fatigue, hot flashes, and breast pain. These side effects are usually mild and will resolve on their own after stopping the medication.

2. Other common side effects (≥1%)

In addition to the common side effects listed above, some patients may also experience symptoms such as headache, dizziness, mood changes, taste changes, vomiting, flatulence (wind), diarrhea, abdominal distension (gastric distension), night sweats, rash or itching, joint pain, pelvic pain, ovarian enlargement, vaginal bleeding, frequent urination, involuntary urination, weight gain, bleeding, itching at the application site, feeling cold or temperature changes, or general discomfort. Although these side effects occur at a low incidence, they still need to be paid attention to by patients and doctors.

When using Cyclogest, patients should strictly follow the doctor's advice and take the medicine according to the correct dosage and usage. Patients should also pay close attention to changes in their own symptoms. If serious side effects occur or symptoms continue to worsen, they should seek medical attention in time and inform the doctor. Through proper use and management, Cyclogest will bring better treatment effects and quality of life to patients with gynecological diseases.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Cyclogest(Progesterone)
Premenstrual syndrome (including symptoms such as tension, irritability, depression, etc.), postpartum depression.
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