Defibrotide stabilizes and protects endothelial cells, inhibits thrombosis, and promotes fibrinolysis, thereby improving coagulation dysfunction, repairing vascular wall damage, and relieving the symptoms of HVOD. Clinical trial results show that compared with historical controls, Defibrotide significantly improves the survival rate of HVOD patients, and has good safety and tolerability. Defibrotide has not yet been approved for marketing in China. Domestic patients need to be cautious when using it and follow the advice and guidance of doctors.
What to pay attention to when using Defibrotide
As an important therapeutic drug, Defibrotide is widely used in clinical practice. For safety reasons, patients need to pay attention to some key matters when using Defibrotide so that patients can be better treated.
Preparation before medication
Before using Defibrotide, patients should read the drug instructions in detail to understand the drug's ingredients, indications, usage and dosage, and possible adverse reactions. At the same time, patients should also consult a doctor to ensure that they have no history of drug allergies, especially those who are allergic to any ingredient in Defibrotide should avoid using it.
Monitoring during medication
During medication, patients should pay close attention to their physical condition. If there is any discomfort or abnormal reaction, they should stop taking the drug immediately and seek medical attention. Patients should also undergo regular blood tests to monitor the efficacy of the drug.
Post-discontinuation treatment
If the condition does not improve significantly after taking the drug for a period of time, the patient should seek medical attention in time and follow the doctor's advice to replace other drugs for treatment. After stopping the drug, the patient should also pay attention to maintaining good living habits to promote physical recovery.
The use of Defibrotide requires patients to strictly follow the doctor's instructions and instructions. Through adequate preparation before medication, close monitoring during medication, and reasonable treatment after discontinuation, the best treatment effect can be achieved.
How to distinguish the authenticity of Defibrotide drugs
After knowing the precautions when using it, you should also understand the precautions before use. With the proliferation of counterfeit drugs on the market, distinguishing the authenticity of drugs has become an important task in the patient's medication process. For key therapeutic drugs such as Defibrotide, patients should be more vigilant to ensure that they are using genuine products.
Check the packaging and label
The packaging of genuine Defibrotide is usually exquisite and clearly printed, and the label should contain key information such as the drug name, specifications, manufacturer, and approval number. Patients can distinguish the authenticity of drugs by comparing the style and content of genuine packaging and labels.
Check the approval number
Each drug has a unique approval number. Patients can check whether the approval number corresponds to Defibrotide through the official website of the State Drug Administration. If it cannot be found or the information is inconsistent, it is likely to be a counterfeit drug.
Observe the properties of the drug
The properties of genuine Defibrotide should be consistent with the description in the instructions, such as color, smell, solubility, etc. Patients can preliminarily judge its authenticity by observing the properties of the drug.
To distinguish the authenticity of Defibrotide, patients need to use a variety of methods, including checking the packaging and labels, checking the approval number, and observing the properties of the drug. Through these methods, patients can greatly improve their ability to distinguish the authenticity of drugs.
Patients' dietary structure recommendations
While using Defibrotide, patients should also pay attention to the adjustment of their dietary structure. A reasonable dietary structure can not only improve the efficacy of the drug, but also reduce the adverse reactions that may be caused by the drug.
Maintain a balanced diet
Patients should consume an appropriate amount of protein, carbohydrates, fats, vitamins and minerals to provide comprehensive nutritional support for the body.
Avoid irritating foods
Spicy, greasy and irritating foods may increase the burden on the liver and are not conducive to disease control. Patients should try to avoid eating these foods.
Intake water in moderation
Maintaining adequate water intake helps promote drug metabolism and reduce drug damage to the kidneys. But you should also avoid drinking too much water to avoid increasing the burden on the liver.
During the use of Defibrotide, a reasonable diet structure can better support drug treatment. These dietary structure recommendations apply not only to the use of Defibrotide, but also to the patient's daily diet.
