Defitelio is an important drug for the treatment of hepatic veno-occlusive disease after hematopoietic stem cell transplantation. Since it has not yet been launched in China and is expensive, special attention should be paid to the legitimacy of the channel and professional medical guidance during the purchase process. This article will provide reference for patients and medical institutions in need from three aspects: purchase channels, precautions and storage methods.
How to buy Defitelio
Defitelio is a special therapeutic drug, and the purchase channels and processes must strictly follow international medical standards. At present, the drug has not been approved for marketing in China, and domestic patients need to obtain it through specific channels.
International purchase channels
The original drug of Defitelio is produced by Jazz Pharmaceuticals in Ireland. It is not available in China and there are no generic drugs. Patients can apply for import through overseas medical institutions or authorized international pharmacies. When purchasing, you need to provide complete prescription certificates and diagnostic information, and entrust a qualified agency to handle customs clearance procedures. Some large hospitals may introduce it through special approval procedures, but they need to confirm with the hospital pharmacy department in advance.
Price and specification information
Actual costs may increase due to transportation, tariffs and service fees. Before purchasing, it is necessary to clarify the dosage requirements and calculate the total amount based on the patient's weight and treatment cycle to avoid waste due to storage conditions.
Obtaining Defibrotide through formal channels is the basis for ensuring drug safety. Patients need to fully communicate with their attending physicians to make sure that the source of the drug is legal and meets treatment needs.
Precautions for purchasing Defibrotide
Purchasing Defibrotide not only involves financial investment, but also concerns treatment safety. The following key points need to be focused on before and after purchase.
Importance of legal channels
There may be illegal purchases or counterfeit drugs on the market, and such channels are extremely risky. Patients should choose institutions with international pharmacy certification and require drug traceability codes and original packaging. After purchase, the product batch number can be verified through the manufacturer's official website to clarify the authenticity of the drug.
Necessity of medical guidance
Defibrotide must be used strictly in accordance with the indications and is suitable for patients with hepatic veno-occlusive disease and organ dysfunction after hematopoietic stem cell transplantation. Before purchase, a hematologist or transplant specialist must assess the condition to confirm whether it meets the medication standards. At the same time, contraindications, such as active bleeding or allergic history, should be checked to avoid serious adverse reactions after medication.
Legal purchase and professional medical evaluation are indispensable. Patients need to develop a treatment plan under the supervision of a doctor to clarify the safety and effectiveness of the medication.
Storage method of Defibrotide after purchase
The correct storage method directly affects the stability and therapeutic effect of Defibrotide. Unopened drugs and prepared solutions must be stored separately according to standards.
Storage temperature and environment
Original unopened Defibrotide must be stored at 20°C-25°C, and a short period of 15°C-30°C is allowed during transportation. The drug should be stored away from light and away from humid or high temperature areas. When stored at home, it can be placed in a cool and dry place, avoiding places with large temperature and humidity fluctuations such as kitchens or bathrooms.
Validity period and use period
Defibrotide is valid for 40 months and must be used before the date marked on the package. If the prepared solution is stored at room temperature, the infusion must be completed within 4 hours; it can be extended to 24 hours under refrigerated conditions. The amount of each preparation should not exceed four doses, and the unused liquid medicine after opening must be discarded and cannot be reused.
Strictly following the storage requirements can maximize the maintenance of drug activity. Patients and caregivers need to check the status of the medicine regularly and stop using it immediately if color changes or sediment are found.
