Ambrisentan is a drug used to treat pulmonary hypertension. Its efficacy, effects and precautions are crucial for patients to use the drug correctly.

Efficacy and effects of Ambrisentan

Pulmonary arterial hypertension (PAH) is a rare but serious disease that causes pulmonary vascular stenosis and increases the burden on the heart. Ambrisentan improves the patient's exercise capacity and delays the deterioration of the disease by dilating the pulmonary blood vessels and reducing pulmonary artery pressure.

Treatment mechanism

Ambrisentan is an endothelin receptor antagonist that can block the action of endothelin, thereby dilating the pulmonary blood vessels and reducing pulmonary artery pressure.

Clinical efficacy

Studies have shown that Ambrisentan can significantly improve the exercise capacity of patients with pulmonary hypertension and delay the deterioration of the disease. After taking Ambrisentan, many patients have improved their ability to carry out daily activities and their quality of life.

After understanding the efficacy and effects of Ambrisentan, patients may be concerned about how to use Ambrisentan when liver and kidney function is impaired.

Precautions for the use of Ambrisentan tablets in patients with impaired liver and kidney function

Patients with impaired liver and kidney function should be particularly cautious when using Ambrisentan tablets, as drug metabolism and excretion may be affected.

Impaired liver function

Ambrisentan tablets are not recommended for patients with moderate or severe liver impairment, as drug metabolism may be affected, increasing the risk of adverse reactions. Patients with mild liver impairment should also use the drug with caution under the guidance of a doctor and have their liver function checked regularly.

Impaired kidney function

Patients with mild or moderate renal impairment usually do not need to adjust the dose of Ambrisentan tablets, and patients with severe renal impairment should use it with caution, as drug excretion may be affected, increasing the risk of drug accumulation in the body.

In addition to the precautions for use in patients with impaired liver and kidney function, patients also need to understand the storage conditions of Ambrisentan in order to better preserve the drug.

Storage conditions of Ambrisentan

Correct storage conditions are important to ensure the quality and efficacy of Ambrisentan.

Storage temperature

Ambrisentan tablets should be stored in an environment of 20°C to 25°C, with an allowable deviation of 15°C to 30°C. Avoid exposing the drug to high temperature or high humidity to avoid affecting the stability and efficacy of the drug.

Storage requirements

Ambrisentan tablets should be stored in a sealed container to avoid transferring the drug to non-original packaging. Patients should pay attention to the expiration date of the drug and avoid using expired drugs. The use of expired drugs may reduce the efficacy of the drug or increase unnecessary risks.

Warm reminder: During the use of Ambrisentan tablets, patients should follow the doctor's prescription and drug instructions, use the drug correctly, and patients should have regular follow-up visits and maintain close communication with the doctor so as to adjust the treatment plan in time. If any discomfort occurs, the patient should report to the doctor in time so that timely treatment and guidance can be obtained.