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   Adverse reactions of Pulmozyme
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Jul 07, 2025

Pulmozyme is a drug used to treat cystic fibrosis. It is an enzyme that breaks down DNA in bacteria and human cells. It reduces the DNA content in thick sputum, making it easier to cough up, thereby improving respiratory function and reducing the risk of lung infection.

Adverse reactions of Pulmozyme

Like other drugs, Pulmozyme may also cause a series of adverse reactions during its use, which may vary from person to person. The following are adverse reactions of the drug:

In clinical trials of patients with cystic fibrosis (CF), adverse reactions caused by Pulmozyme treatment are more common. Among patients treated with this drug, adverse reactions with an incidence of more than 3% mainly include voice changes, pharyngitis, rash, laryngitis, chest pain, conjunctivitis, rhinitis, etc. In addition, some patients may also experience adverse reactions such as a decrease in FVC (forced vital capacity) of more than 10%, fever, and dyspnea.

In the face of side effects such as pharyngitis, rash, and laryngitis, patients can consult a doctor in time, treat them correctly, and take appropriate countermeasures according to the doctor's advice to relieve the discomfort caused by side effects.

Countermeasures for side effects of Dornase Alfa(Pulmozyme)

By taking appropriate measures, such as strictly following the doctor's instructions and paying attention to the observation of adverse reactions, the impact of side effects on the patient's quality of life can be reduced, while ensuring the effectiveness and safety of drug treatment.

Strictly follow the doctor's instructions

Patients should use the drug correctly according to the doctor's instructions and avoid increasing or decreasing the dose or changing the method of medication on their own. At the same time, they should seek medical attention regularly to evaluate the treatment effect and adverse reactions.

Pay attention to the observation of adverse reactions

During the use of the drug, patients should pay close attention to their own conditions, especially adverse reactions related to the drug. If any discomfort or suspected allergic reaction occurs, the drug should be stopped immediately and medical treatment should be sought in time.

Take appropriate relief measures

For mild adverse reactions, such as voice changes, pharyngitis, rash, etc., patients can take appropriate relief measures under the guidance of doctors, such as drinking more water, keeping the mouth clean, using anti-allergic drugs, etc.

Seek medical attention immediately

For serious adverse reactions, such as dyspnea, facial swelling, rash, urticaria, etc., patients should seek medical attention immediately and seek help from doctors. Doctors will take appropriate treatment measures according to the specific situation to ensure the safety of patients.

Before use, please make sure you have fully understood the indications, usage, dosage and possible adverse reactions of Pulmozyme. If you have any questions, please consult your doctor or pharmacist in time.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Dornase Alfa(Pulmozyme)
Pulmozyme is indicated for inhalation in children and adults with cystic fibrosis (CF) in combination with standard therapy to improve lung function.
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