Elglustat(Cerdelga) is a drug used to treat Gaucher disease type 1.The drug is mainly purchased through overseas channels, such as the original drug from Sanofi in France, and the price is relatively high.
How to buy Elglustat(Cerdelga)?
Since Elglustat is not yet available in China, patients need to purchase it through overseas channels. The following are specific purchase methods and suggestions.
Overseas purchase channels
Currently, the original drug of Elglustat(Cerdelga) is produced by Sanofi in France. Patients can buy it through overseas medical institutions or pharmacies, but they need to make sure that the channels are formal to avoid buying counterfeit drugs. It is recommended to consult a professional doctor or pharmacist before purchasing to understand the specific specifications and dosage requirements of the drug.
Domestic alternatives
Since there are no generic drugs on the market in China, if patients cannot afford the high cost of original drugs, they can consider participating in clinical trials or applying for charitable assistance projects. Some international organizations or pharmaceutical companies will provide drug assistance to eligible patients to reduce the financial burden.
When purchasing Elglustat, you need to carefully choose the channel to avoid ignoring the authenticity and safety of the drug due to price or convenience. Next, we will discuss the precautions when purchasing.
Precautions for purchasing Elglustat
When purchasing Elglustat, patients need to pay attention to the indications, dosage adjustments and potential risks of the drug to clarify the safety of medication.
Indications and dosage adjustments
Elglustat is suitable for adult patients with Gaucher disease type 1 who are extensive metabolites, intermediate metabolites or poor metabolites of FDA-approved CYP2D6 metabolism testing. The dose needs to be adjusted according to the patient's metabolic status, and the dose needs to be reduced when taking strong CYP3A inhibitors or CYP2D6 inhibitors. It is recommended to use the drug under the guidance of a doctor and avoid self-adjustment.
Adverse reactions and contraindications
Common adverse reactions include fatigue, headache, nausea, etc., which may cause arrhythmias in severe cases. It is contraindicated for patients with a history of heart disease, long QT syndrome or who are taking specific antiarrhythmic drugs. You need to fully understand your health status before purchasing to avoid medication risks.
Understanding the precautions of drugs is a prerequisite for safe medication. At the same time, a reasonable diet structure can also help patients better exert the efficacy of drugs. Next, we will discuss the dietary recommendations for patients with Elglustat.
Dietary structure of patients with Elglustat
Diet has a certain impact on the efficacy of Elglustat, and patients need to pay special attention to the interaction between food and drugs.
Avoid strong CYP3A inhibitors
Grapefruit and grapefruit juice are strong CYP3A inhibitors, which will significantly increase the blood concentration of Elglustat, leading to an increased risk of adverse reactions. Patients should avoid eating such foods during medication and choose other fruits instead.
Balanced diet and nutrition
Patients with Gaucher disease often have malnutrition problems. It is recommended to consume high-protein, low-fat foods, such as lean meat, fish and vegetables, to maintain good health. At the same time, maintaining adequate water intake helps drug metabolism.
A reasonable diet structure can not only improve the efficacy of drugs, but also improve the overall health of patients. Combined with scientific medication and dietary management, patients with Gaucher disease can better control their condition and improve their quality of life.
