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   How to relieve the side effects of Naldemedine?
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Jul 02, 2025

Naldemedine is a drug used to treat constipation caused by opioids. Although it is effective, it may also be accompanied by some side effects, such as abdominal pain, diarrhea, nausea, etc. Understanding how to relieve these side effects, properly store the drug, and adjust the diet structure is important for the patient's treatment experience.

How to relieve the side effects of Naldemedine?

Common side effects of Naldemedine include abdominal pain, diarrhea, nausea, etc., which may affect the patient's quality of life. These discomforts can be effectively relieved through reasonable methods.

Methods to relieve abdominal pain

Abdominal pain is one of the more common side effects of Naldemedine. Patients can adjust the time of taking the medicine and choose to take the medicine after meals to reduce irritation to the gastrointestinal tract. At the same time, appropriate hot compresses or gentle massage of the abdomen can also relieve pain. If the abdominal pain persists or worsens, you should seek medical attention in time.

Management measures for diarrhea

Diarrhea may be caused by the effect of Naldemedine on the intestines. Patients should maintain adequate water intake to avoid dehydration. Choosing low-fiber, easily digestible foods in the diet, such as white porridge, bananas, etc., can help alleviate symptoms. If diarrhea is severe, antidiarrheal drugs can be used under the guidance of a doctor.

Through the above methods, patients can effectively alleviate the side effects of Naldemedine and improve the comfort of treatment. Next, we will discuss how to properly store Naldemedine to confirm the efficacy of the drug.

Storage method of Naldemedine

The correct storage method is important to maintain the efficacy of Naldemedine. If the drug is not stored properly, it may reduce the efficacy or even fail.

Temperature and light control

Naldemedine should be stored in an environment of 20 to 25°C and avoid direct sunlight. Light and high temperature may destroy the structure of the drug, so it is recommended to store the drug in a cool and dry place or in a light-proof container.

Moisture-proof and packaging integrity

A humid environment may affect the stability of Naldemedine. The drug should be sealed and stored to avoid moisture. At the same time, keep the original packaging intact and do not transfer the drug to other containers to prevent contamination or damage.

Reasonable storage methods can extend the shelf life of Naldemedine and clarify the treatment effect. Finally, we will pay attention to the patient's dietary structure to provide more support for treatment.

Dietary structure of patients taking Naldemedine

A reasonable dietary structure can help reduce the side effects of Naldemedine and improve the overall treatment effect.

Choice of high-fiber foods

Although Naldemedine is used to treat constipation, excessive intake of high-fiber foods may increase the burden on the gastrointestinal tract. Patients should consume fiber in moderation, such as oats, whole wheat bread, etc., and avoid consuming a large amount at one time.

Water and electrolyte balance

Adequate water intake is beneficial for preventing constipation and diarrhea. Patients should drink enough water every day and supplement electrolytes appropriately, such as drinking light salt water or beverages containing electrolytes to maintain body balance.

By adjusting the dietary structure, patients can better cooperate with the treatment of Naldemedine and reduce the occurrence of discomfort symptoms. A reasonable diet combined with drug management will bring better results for treatment.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Naldemedine(Symproic)
Opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
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