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   How to buy Naldemedine?
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Jul 02, 2025

The main ingredient of Naldemedine is Symproic. As an effective drug for treating constipation, it is especially suitable for patients with constipation caused by long-term use of opioids.

How to buy Naldemedine?

Since the drug has not yet been launched in China, patients need to carefully understand and choose the purchase channel.

Hospital pharmacy

Patients can buy Naldemedine at the pharmacy of a regular hospital with a prescription issued by a doctor. This method is the most direct and the quality of the drug is guaranteed.

Professional pharmacy

Some large chain pharmacies or professional pharmacies may also sell Naldemedine. Patients should consult the pharmacy staff before purchasing to confirm the source and authenticity of the drug.

Cross-border medical services

For Naldemedine, which has not yet been widely launched in China, patients can also obtain it through cross-border medical service projects. This usually involves professional overseas medical institutions, but it is necessary to pay attention to choosing a reputable channel and understand the relevant laws and regulations of the country on imported drugs.

When purchasing Naldemedine, patients should choose regular channels. The price of Naldemedine in different channels and regions may vary. Patients should choose rationally to avoid being misled by high-priced or low-priced drugs.

Basic pharmacological effects of Naldemedine

After knowing how to buy Naldemedine, understanding the basic pharmacological effects of Naldemedine will help patients better understand and use the drug, thereby maximizing its therapeutic effect.

Relieve constipation

Naldemedine mainly blocks μ-opioid receptors and reduces the inhibitory effect of opioids on intestinal peristalsis, thereby accelerating the transmission of intestinal contents and relieving constipation symptoms.

Regulate intestinal function

Naldemedine can also regulate the secretion and peristalsis of the intestine, reduce the production and accumulation of intestinal fluid, and further promote smooth defecation.

Safety

Naldemedine has high specificity and mainly acts on the intestine. It has little effect on the central nervous system, so it is safer.

Naldemedine blocks μ-opioid receptors, regulates intestinal function, and effectively relieves constipation symptoms. Its pharmacological effects are clear, its mechanism of action is clear, and its safety is high, providing patients with new treatment options.

Contraindications of Naldemedine

During the use of Naldemedine, patients need to pay attention to dietary taboos to avoid affecting the efficacy of the drug or increasing the risk of adverse reactions.

High-fat foods

High-fat foods may increase the burden on the intestines, delay the absorption and metabolism of the drug, and thus affect the efficacy of Naldemedine. During the use of Naldemedine, patients should try to avoid eating high-fat foods.

Spicy foods

Spicy foods may irritate the intestines and aggravate constipation symptoms, which is contrary to the therapeutic effect of Naldemedine. Therefore, patients should also avoid eating spicy foods.

Alcohol

Alcohol may interfere with the metabolic process of the drug and increase the risk of adverse reactions. During the use of Naldemedine, patients should strictly abstain from alcohol.

During the use of Naldemedine, in addition to paying attention to diet, patients should also maintain a light diet, drink enough water and regular eating habits, which will help promote the absorption and metabolism of the drug and improve the therapeutic effect.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Naldemedine(Symproic)
Opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
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