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   Instructions for Ritlecitinib: action and efficacy, dosage, side effects, precautions
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Jun 30, 2025

Ritlecitinib is an innovative oral kinase inhibitor that offers a new treatment option for patients with severe alopecia areata. This article will start from the instructions of Ritlecitinib and elaborate on its role and efficacy, dosage, as well as potential side effects and precautions, aiming to provide patients with comprehensive and concise medication guidance.

Instructions for Ritlecitinib

Ritlecitinib was launched in the U.S. and Japan in June 2023, followed by approval by the China Food and Drug Administration in October 2023 for the treatment of severe alopecia areata in adults and adolescents aged 12 years and older.

Basic Information

Ritlecitinib is a kinase inhibitor that exerts therapeutic effects by inhibiting JAK3 and TEC targets. The capsule has a yellow capsule with a blue cap, and the bottle and cap are stamped with specific logos.

Listing & Medicare

Although it has been marketed at home and abroad, it has not yet been included in the scope of national medical insurance reimbursement, and patients need to purchase it at their own expense.

Ritlecitinib is an oral kinase inhibitor developed by Pfizer, mainly used for the treatment of severe alopecia areata, patients need to understand its basic information and market medical insurance in order to use it rationally.

Actions and efficacy of Ritlecitinib, dosage and dosage

Ritlecitinib regulates the immune system by specifically inhibiting JAK3 and TEC kinase activity, thereby improving symptoms in patients with severe alopecia areata.

Functions and efficacy

Ritlecitinib is indicated for the treatment of severe alopecia areata in adults and adolescents aged 12 years and above, and improves the quality of life of patients by modulating the immune response, promoting hair growth, and improving the quality of life of patients.

Dosage

The recommended dose is 50mg litexinib capsules orally once daily, with or without a meal. Capsules should be swallowed whole, avoiding crushing, splitting, or chewing. If a dose is missed, it should be retaken as soon as possible, but if it is less than 8 hours before the next dose, the missed dose should be skipped and continue to take as usual.

Ritlecitinib exerts efficacy in the treatment of severe alopecia areata by inhibiting the activity of specific kinases. Patients should follow their doctor's instructions and take their medications on time and in the right amount.

Side effects and precautions for Ritlecitinib

Although litextinib offers a new treatment option for patients with severe alopecia areata, it is still important to pay attention to its potential side effects and precautions during use.

side effect

Common side effects of Ritlecitinib include headache, diarrhea, acne, rash, etc., with a higher incidence. Adverse reactions such as urticaria, folliculitis, fever, and atopic dermatitis may also occur. Patients should pay close attention to the body's reaction during use, and seek medical attention in time if they are not feeling well.

Precautions

Before taking Ritlecitinib, patients should inform their doctor about their allergies, medical history, and medications. Pregnant women, lactating women, pediatric patients, elderly patients and patients with liver injury should be used with caution under the guidance of a doctor. It is not recommended to use it in combination with other JAK inhibitors and biological immunomodulators, so as not to increase the risk of adverse reactions.

Although it has good efficacy, patients still need to pay attention to its potential side effects and precautions during use. By following the doctor's instructions and using drugs rationally, the efficacy of the drug can be maximized and the risk of adverse reactions can be reduced.

Note: For internal discussion among medical personnel only. For specific medication, please consult the attending physician. Drug information may change over time. For the latest information, we recommend adding a medical consultant or consulting for free online.
Ritlecitinib(Litfulo)
Adolescents aged 12 years and older, as well as adult patients, with alopecia areata.
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