Zyvox(Linezolid) Instructions:Uses,Dosage, Side Effects

Nosocomial pneumonia

Community-acquired pneumonia, including concurrent bacteremia

Complicated skin and skin structure infections (e.g., diabetic foot infections without osteomyelitis)

Uncomplicated skin and skin structure infections

Vancomycin-resistant Enterococcus faecium infections, including concurrent bacteremia

Adults and adolescents (≥12 years): 600 mg IV or orally every 12 hours for most indications; 400 mg orally every 12 hours for uncomplicated skin infections.

Pediatric patients (birth to 11 years): 10 mg/kg every 8 hours IV or orally; for uncomplicated skin infections in children 5–11 years: 10 mg/kg every 12 hours orally.

Neonates (<7 days, preterm): 10 mg/kg every 12 hours, with possible adjustment to every 8 hours if clinically indicated.

Treatment duration ranges from 10 to 28 days depending on infection type and severity.

No dosage adjustment is required when switching from IV to oral administration.