bictegravir/emtricitabine/tenofovir alafenamide(Biktarvy)
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Xagrid(bictegravir/emtricitabine/tenofovir alafenamide) Instructions:Uses,Dosage, Side Effects
BIKTARVY contains three active components: bictegravir, which is an integrase strand transfer inhibitor (INSTI); emtricitabine, a nucleoside reverse transcriptase inhibitor (NRTI); and tenofovir alafenamide (TAF), another NRTI. It is formulated as an oral tablet and serves as a complete regimen, meaning it does not require additional antiretroviral agents.
The medication is designed to suppress HIV-1 replication and is available in different strengths to accommodate various patient weights, starting from 14 kg. It was initially approved in the U.S. in 2018 and is intended for long-term management of HIV-1, helping to reduce viral load and support immune function.
Generic name
bictegravir/emtricitabine/tenofovir alafenamide(Biktarvy)
English name
bictegravir/emtricitabine/tenofovir alafenamide
Alternative Names
Biktarvy
Indications
Treatment-naïve adults and pediatric patients (≥14 kg) with HIV-1.
Virologically suppressed patients switching from a stable antiretroviral regimen with no known resistance to BIC or tenofovir.
Patients with antiretroviral treatment history who are not virologically suppressed, provided there are no known resistance-associated substitutions to INSTIs, FTC, or tenofovir.
Therapeutic Target
HIV-1 integrase strand transfer inhibitor (INSTI) and nucleoside reverse transcriptase inhibitors (NRTIs)
Active Ingredients
Bictegravir (BIC), Emtricitabine (FTC), Tenofovir alafenamide (TAF)
specifications
50mg/200mg/25mg * 30 tablets/box
Dosage and Administration
Adults and pediatric patients ≥25 kg: one 50/200/25 mg tablet once daily.
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