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MEXTOVI(Binimetinib)

Acetylcysteine Injection, FLUIMUCIL, Acetylcysteine InjectionAcetylcysteine Injection, FLUIMUCIL, Acetylcysteine InjectionAcetylcysteine Injection, FLUIMUCIL, Acetylcysteine Injection

Reference price:

Manufacturer:

‌Pierre Fabre

Formulation:

TABLET

Validity period:

24 months

Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

MEXTOVI(Binimetinib) Instructions:Uses,Dosage, Side Effects

MEXTOVI is the brand name for the active substance binimetinib, a reversible inhibitor of MEK1 and MEK2 kinases. It is formulated as 15 mg film-coated tablets for oral use. This targeted therapy is designed to interrupt the RAS/RAF/MEK/ERK signaling pathway and is exclusively used in combination with encorafenib, a BRAF inhibitor, for the treatment of eligible patients with confirmed BRAF V600E or V600K mutations.

Generic name

MEXTOVI(Binimetinib)

English name

Binimetinib

Alternative Names

MEXTOVI

Drug prices

Indications

Treatment of patients with unresectable or metastatic melanoma harboring a BRAF V600E or V600K mutation, as confirmed by an FDA-approved test.

Treatment of adult patients with metastatic NSCLC with a BRAF V600E mutation, as detected by an FDA-approved test.

Must be used in combination with encorafenib.

Therapeutic Target

MEK1 and MEK2 kinases (mitogen-activated extracellular signal-regulated kinase 1 and 2)

Active Ingredients

Binimetinib

Dosage form

TABLET

specifications

15mg * 45 tablets/box

Description

Dosage and Administration

45 mg orally twice daily (approximately 12 hours apart) in combination with encorafenib.

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