Cenobamat(Xcopri)
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Reference price:
Manufacturer:
SK LIFE
Formulation:
TABLET
Validity period:
24 months
Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

Cenobamate is a medication used in the management of partial-onset seizures in adults. It works by modulating both sodium channels and GABA receptors in the brain, making it effective in reducing the frequency of seizures. The drug is known for its high bioavailability and is typically administered orally.  

The treatment begins with a low dose, which is titrated gradually. Its safety profile includes potential risks such as QT interval shortening and somnolence, so careful monitoring is advised. It is not recommended for individuals with certain heart conditions, such as familial short QT syndrome.  

This manual consolidates the key details regarding Cenobamate from the available documentation.

Generic name

Cenobamat(Xcopri)
English name
Cenobamat
Alternative Names
Xcopri
Drug prices
Indications

XCOPRI is indicated for the treatment of partial-onset seizures in adult patients. It is used to help reduce the frequency and severity of seizures in individuals suffering from epilepsy characterized by partial-onset seizures.

Therapeutic Target
epileptic neuronal circuits
Active Ingredients
Cenobamate
Dosage form
TABLET
specifications
25mg*30 tablets/box
Description

XCOPRI (Cenobamate) is an antiepileptic drug (AED) developed to treat partial-onset seizures in adults. It has a dual mechanism of action: it enhances GABAergic inhibition and inhibits sodium channel activity, both of which help to stabilize neuronal firing and reduce the likelihood of seizures. The drug has demonstrated efficacy in clinical trials, showing significant seizure reduction in patients with partial-onset epilepsy.

Dosage and Administration

The recommended initial dosage is 12.5 mg once daily, which can be titrated upward to a maintenance dose of 200 mg once daily.

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