Sparsentan(Filspari)
Acetylcysteine Injection, FLUIMUCIL, Acetylcysteine InjectionAcetylcysteine Injection, FLUIMUCIL, Acetylcysteine InjectionAcetylcysteine Injection, FLUIMUCIL, Acetylcysteine Injection
Reference price:
Manufacturer:
Travere Therapeutic
Formulation:
TABLET
Validity period:
24 months
Reminder: The outer packaging is for reference only, please purchase and use under the guidance of a pharmacist. For read by medical and pharmaceutical professionals only.

Sparsentan, marketed as FILSPARI, is used for the management of primary IgAN, a condition that causes kidney damage. By antagonizing both endothelin type A and angiotensin II type 1 receptors, it helps to slow kidney function decline and reduce proteinuria in affected patients.

It is important for patients to undergo regular monitoring of liver function and to follow contraception guidelines due to the drug's risks of hepatotoxicity and embryo-fetal toxicity. Sparsentan offers a promising therapy for IgAN, but its use requires strict adherence to safety protocols to minimize the risk of adverse effects.

Generic name

Sparsentan(Filspari)
English name
Sparsentan
Alternative Names
Filspari
Drug prices
Indications

FILSPARI® (Sparsentan) is indicated for the treatment of focal segmental glomerulosclerosis (FSGS), a rare kidney disorder that leads to nephrotic syndrome. This medication is specifically used in patients who have FSGS and are at risk of progressive kidney disease.

Therapeutic Target
Endothelin A receptor,Angiotensin II type 1 receptor
Active Ingredients
Sparsentan is the active pharmaceutical ingredient (API) in FILSPARI®.
Dosage form
TABLET
specifications
400mg*30tablets/box
Description

FILSPARI® (Sparsentan) is a dual endothelin and angiotensin II receptor antagonist used to treat focal segmental glomerulosclerosis (FSGS). By targeting these receptors, FILSPARI® works to reduce proteinuria, improve kidney function, and delay progression to kidney failure in FSGS patients. The drug is dispensed in tablet form for oral administration.

FILSPARI® is subject to a Risk Evaluation and Mitigation Strategy (REMS) due to its potential risks, including hepatotoxicity and embryo-fetal toxicity. It is available only through restricted distribution channels.

Dosage and Administration

The recommended starting dose of FILSPARI® is 200 mg once daily.

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