Sandostatin(Octreotide Acetate Injection)
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BYNFEZIA PEN (octreotide acetate) is a somatostatin analogue used primarily for the treatment of hormone-related conditions, including acromegaly and certain types of tumors such as metastatic carcinoid and VIPomas. It works by inhibiting excessive secretion of growth hormone and other hormones, alleviating symptoms like flushing and diarrhea. The drug is administered via subcutaneous injection, which for patient self-administration.
BYNFEZIA PEN provides a critical management option for patients who have not responded well to surgery, irradiation, or other pharmacological treatments. It is a versatile and effective therapeutic tool in the management of these complex endocrine and gastrointestinal disorders.
Generic name
Sandostatin(Octreotide Acetate Injection)
English name
Octreotide Acetate Injection
Alternative Names
Sandostatin
Indications
1. Acromegaly: To reduce elevated levels of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in patients who are unresponsive to or ineligible for surgical resection, pituitary irradiation, or bromocriptine mesylate.
2. Metastatic Carcinoid Tumors: For symptomatic treatment of severe diarrhea and flushing episodes.
3. Vasoactive Intestinal Peptide Tumors (VIPomas): For the management of profuse watery diarrhea associated with VIP-secreting tumors.
Therapeutic Target
Somatostatin receptors in the endocrine and neuroendocrine systems, particularly in pituitary and gastrointestinal tract cells secreting GH, VIP, and other peptides.
Active Ingredients
Octreotide acetate (synthetic somatostatin analog)
specifications
30mg*1vial/box
Description
Octreotide is a synthetic long-acting cyclic octapeptide analog of the naturally occurring hormone somatostatin. It mimics the pharmacologic effects of somatostatin by inhibiting the secretion of several hormones including GH, insulin, glucagon, and various gastrointestinal peptides.
Dosage and Administration
Route: Subcutaneous injection into the abdomen, upper outer arm, or front of thighs; rotate injection sites.Administer at room temperature. Visually inspect for clarity and absence of particles.
1. Acromegaly: Initial dose: 50 mcg three times daily for 2 weeks; maintenance: 100–500 mcg three times daily.
2. Carcinoid Tumors: 100–600 mcg daily in 2–4 divided doses.
3. VIPomas: 200–300 mcg daily in 2–4 divided doses.
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