The dosage of Cerezyme is patient-specific, requiring intravenous administration under medical supervision.

Individualized Intravenous Enzyme Replacement Therapy

The recommended dosage of Cerezyme varies depending on disease severity, ranging from 2.5 units/kg three times per week to 60 units/kg once every two weeks. The infusion should be administered intravenously over 1 to 2 hours in a clinical setting equipped to manage hypersensitivity reactions. For patients weighing less than 18 kg, the infusion should be administered over 2 hours. Dosage adjustments are based on clinical response, including hematologic and visceral improvements. The preparation of Cerezyme requires reconstitution with sterile water for injection, followed by dilution in 0.9% sodium chloride solution.